Ernie and Bert (are we supposed to name another Harry Potter duo?)

haryr and Ron, or Harry and hermione and finally, me and fandom addiction

Anakin and Obi-wan, R2 and Threepio, Chewie and Han.

I totally agree. FRED AND GEORGE FOR LIFE!!!

McGonagall and 'Piertotum Locomotor'

There is no other iconic duo other than them

Eda and Lilith clawthorne