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"There are plenty of eye-witness accounts. Just because you're so narrow-minded you need to have everything shoved under your nose before you–"
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"Harry, your eyesight really is awful."
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Left handed nazle powder is a dust which presumably is used in potions, and causes the consumer to become left handed. A bottle of this substance was located in the potions classroom at Hogwarts School of Witchcraft and Wizardry from c.1996 onwards. The said sample is described as belonging to the Hogwarts Apothecary Department.